1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or review is critical for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their study is significant for optimizing the output system and ensuring higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to take care of breast most cancers, and these intermediates are involved with its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Employed in the therapy of breast most cancers. Different intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis CAS NO. 155405-80-4 of paclitaxel, a chemotherapy drug helpful in treating cancers which include ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have several applications, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of varied gluconic acid derivatives, which happen to be Employed in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: 17-Diol 17-Acetate A precursor from the synthesis of canagliflozin, a medication applied to deal with sort two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).